Grants

COVID-19 Research

The research community in Singapore contributes to the fight against COVID-19 and initiates new research projects that aim to support the disease outbreak management and control in Singapore.

The following central depository comprises key information on all COVID-19 related research projects and is made accessible to the entire research community. The objective is to keep all researchers abreast of ongoing COVID-19 research work, so as to promote greater collaboration and reduce inadvertent duplicative effort, particularly where these involve the use of limited and precious resources such as clinical samples and expensive equipment.

List of Projects Funded under NMRC COVID-19 Research Fund

S/N

Project Title

PI

Institution

Grant Reference Number

1

Understanding the clinical features and immune-pathogenesis of COVID-19

Barnaby Young

TTSH

MOH-000415

2

Integrating environmental, virological and population approaches to understand the transmission of COVID-19

Mark Chen I-Cheng

TTSH

MOH-000416

3

Serological investigation of 2019-CoV infection

Wang Linfa

Duke-NUS

MOH-000417

4

Modelling and analytics for the outbreak of the novel coronavirus in Singapore

Alex R Cook

NUS

MOH-000418

5

Media communication, online falsehoods and population responses surrounding the novel coronavirus disease crisis (COVID-19) in Singapore

May Oo Lwin

NTU

MOH-000404

6

A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults

David Lye

TTSH

MOH-000419

7

Establishment of COVID-2019 animal infection models

Danielle Anderson

Duke-NUS

MOH-000413

8

Investigating airway cell tropism, responses and entry receptor of COVID-19 virus (SARS-CoV-2) in elucidating its transmission and pathogenesis in the airway

Wang De Yun

NUS

MOH-000408

9

Lung Organoids: A tool of the fourth industrial revolution to study COVID-19 pathogenesis

Sanjay Haresh Chotirmall

NTU

MOH-000409

10

Covid-19 Virtual Disease health System Outcomes model for Singapore (CoViD- SOS)

Marcus Ong

SGH

MOH-000410

11

Environmental SARS-CoV-2 surveillance in Singapore built environment

Stephan Christoph Schuster

NTU

MOH-000411

12

Coronavirus disease-19: A seroepidemiology study among healthcare workers in Singapore (the COVSEP study)

Seet Chee Seong Raymond

NUS

MOH-000407

13

Rapid Cellulose-Based Serological and Diagnostic Tests for COVID-19

Peter Rainer Preiser

CREATE-SMART

MOH-000412

14

The SARS-CoV-2 Antibody Initiative

Paul MacAry

NUS

MOH-000420

15

Using GM-CSF as a Host Directed Therapeutic against COVID-19 - A
Phase 2 Investigator Initiated Trial

Jenny Low

SGH

MOH-000423

16

A Point-of-care Rapid Antigen Test Kit for the Detection of SARS-Cov-2 Infection

Lim Chwee Teck

NUS

MOH-000445

17

New MHC technologies to identify and analyze SARS-CoV-2-specific CD8+ T cells

Nicholas Robert John Gascoigne

NUS

MOH-000438

18

Targeting Endothelial Dysfunction to Ameliorate Cytokine Storm in COVID-19

Lena Ho

Duke-NUS

MOH-000439

19

Direct detection of COVID-19: integrating molecular switches with automated microfluidics

Huilin Shao

NUS

MOH-000440

20

Nanoparticle-based Serological Assays for COVID-19 using Linear B-Cell Epitopes from Spike and Nucleocapsid Proteins from SARS-CoV-2

Xiaodi Su

IMRE

MOH-000441

21

Duration of immune response and identification of markers of sequelae in SARS-CoV-2 recovered patients

RENIA LAURENT

SIgN

MOH-000463

22

Mitigating SARS-CoV-2 transmission through expiratory droplet control and environmental intervention

Kwok Wai Tham

NUS

MOH-000443

23

Phase 1 dose-finding study of Irinotecan to reduce systemic inflammation in COVID-19

Anand Jeyasekharan

NUH

MOH-000444

24

RESILIENCE UNDER FIRE: ROBUST KIT COMPONENTS FOR COVID-19 DETECTION DEVELOPED AND MADE IN SINGAPORE

Farid John Ghadessy

p53 Lab

MOH-000464

25

Non-invasive liquid biopsies for monitoring Covid-19 infection, co-infections and host response

Shawn Hoon

IBN

MOH-000466

26

Chimeric Antigen Receptor-Natural Kill Cell Therapy to Ameliorate Macrophage Activation Syndrome in Severe COVID-19

Wang Shu

NUS

MOH-000465

27

Mathematical modelling for assessment and optimal deployment of COVID-19 vaccination in Singapore

Hannah Clapham

NUS

MOH-000442

28

Paper-based neutralization test for rapid assessment of COVID-19 immunoprotective profile

Peter Rainer Preiser

CREATE-SMART

MOH-000467

29

A Platform for Vaccine Development in Singapore against Coronaviridae and other Infectious Disease Outbreaks

Francesca Lim

SGH

MOH-000467

30

Rapid Detection of SARS-CoV-2 RNA in Patients

Jackie Ying

NanoBio Lab

MOH-000467

31

DR COVID – A Multi-lingual Artificial Intelligence Virtual System with Audio-Visual Technology for COVID-19

Daniel Ting

SERI

MOH-000467

32

Mental Health Triage and Resource Recommendation System for Individuals with COVID-related Mental Health Concerns

Ilya Farber

IHPC

MOH-000467

33

A*STAR Fortitude (PCR Based Molecular Diagnostic Assay Development)

Masafumi Inoue

EDDC

MOH-000468

34

PCR-Based Molecular Diagnostic Kit Productisation (A*STAR Fortitude)

Weng Ruifen

DxD

MOH-000468

35

Diagnostics: Novel exponential amplification assay (Isothermal Amplification Assay for COVID-19 Detection)

Jackie Ying

NBL/DxD

MOH-000468

36

Serological POCT: Antigen based Detection via SARS mAb

Tan Yee Joo

IMCB/DxD

MOH-000468

37

Assays to Differentiate Between Corona Viruses

Lisa Ng

SIgN

MOH-000468

38

COVID19 Neutralizing Antibody Development

Wang Cheng I

SIgN

MOH-000468

39

Masks: Reusable Medical Mask Development and Small Scale Production

Chng Shuyun

SIMTech/ARTC

MOH-000468

40

Masks: Mask Testing Capabilities

Liu Songlin/Yang Yi Yan

IMRE/IBN/NMC

MOH-000468

41

Transmission Potential of Asymptomatic SARS-CoV-2-infected Persons

Ng Oon Tek

TTSH

MOH-000469

42

A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients with COVID-19

Barnaby Young

TTSH

MOH-000469

43

Persistence of Immune Response in Migrant Workers with Mild or Asymptomatic COVID-19 Infection

Hsu Li Yang

NUS

MOH-000499

44

Portable SERS-based Breathalyzer for Rapid and Online COVID-19 Detection and Surveillance

Ling Xing Yi

NTU

MOH-000503

 45  Singapore COVID-19 Vaccine Immune Response and Protection Study (SCOPE) Barnaby Young  TTSH  MOH-000578
 46 Vaccine communication and messaging:  Addressing COVID-19 vaccine hesitancy and promoting population acceptance    May Oo Lwin  NTU MOH-000576 
47   A Network Ecological Approach for COVID-19 Surveillance and Infection Control among Migrant Workers in Singapore Issac Lim   NHG MOH-000579 
48   Prime-boost vaccine strategy for increased immunogenicity and cross-variant protection (PRIBIVAC) Laurent Renia   A*STAR ID Labs MOH-000586 
 49  Portable SERS-based Breathalyzer for Rapid and Online COVID-19 Detection and Surveillance (Phase 2) Ling Xing Yi   NTU  MOH-000584
50   Non-Invasive and Rapid Screening of COVID-19 Using Volatile Organic Compounds (VOCs) in Exhaled Breath   Freddy Boey  NUS  MOH-000603
51  Development of pan-sarbecovirus vaccine candidates to combat COVID-19 and future coronavirus pandemics  Wang Linfa Duke-NUS  MOH-000696 
52  Determining the impact of SARS-CoV-2 variants and vaccination on close-contact attack rates and acquisition risk factors  Ng Oon Tek TTSH  MOH-000717 
53  Pathophysiologic Mechanism for MYOcarditis in COVID19 VAccinations (MYOVAx study)  Yeo Khung Keong NHCS   MOH-000718
54  UV-C solution for air disinfection in confined spaces  May Win Naing  SIMTech  MOH-000721
55  Heterologous Prime-Boost-Boost Vaccine Combinations for Long-Term Humoral and Cellular Immunity Against COVID-19   Barnaby Young  TTSH MOH-000736 
56  Singapore COVID-19 Vaccination in Children (SGCoVaC) Yung Chee Fu  KKH   MOH-000769